Re-sequencing of the APOL1-APOL4 and MYH9 gene regions in African Americans does not identify additional risks for CKD progression

BACKGROUND: APOL1 G1 and G2 nephropathy risk variants are associated with non-diabetic end-stage kidney disease (ESKD) in African Americans (AAs) in an autosomal recessive pattern. Additional risk and protective genetic variants may be present near the APOL1 loci since earlier age ESKD is observed i...

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Publicat a:Am J Nephrol
Autors principals: Hawkins, Gregory A., Friedman, David J., Lu, Lingyi, McWilliams, David R., Chou, Jeff W., Sajuthi, Satria, Divers, Jasmin, Parekh, Rulan, Li, Man, Genovese, Giulio, Pollak, Martin R., Hicks, Pamela J., Bowden, Donald W., Ma, Lijun, Freedman, Barry I., Langefeld, Carl D.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589514/
https://ncbi.nlm.nih.gov/pubmed/26343748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000439448
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