Differential Effects of MYH9 and APOL1 Risk Variants on FRMD3 Association with Diabetic ESRD in African Americans

Single nucleotide polymorphisms (SNPs) in MYH9 and APOL1 on chromosome 22 (c22) are powerfully associated with non-diabetic end-stage renal disease (ESRD) in African Americans (AAs). Many AAs diagnosed with type 2 diabetic nephropathy (T2DN) have non-diabetic kidney disease, potentially masking dete...

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Main Authors: Freedman, Barry I., Langefeld, Carl D., Lu, Lingyi, Divers, Jasmin, Comeau, Mary E., Kopp, Jeffrey B., Winkler, Cheryl A., Nelson, George W., Johnson, Randall C., Palmer, Nicholette D., Hicks, Pamela J., Bostrom, Meredith A., Cooke, Jessica N., McDonough, Caitrin W., Bowden, Donald W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116917/
https://ncbi.nlm.nih.gov/pubmed/21698141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002150
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