Lack of Association of the APOL1 G3 Haplotype in African Americans with ESRD

Apolipoprotein L1 gene (APOL1) G1 and G2 variants are strongly associated with progressive nondiabetic nephropathy in populations with recent African ancestry. Selection for these variants occurred as a result of protection from human African trypanosomiasis (HAT). Resequencing of this region in 10...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Palmer, Nicholette D., Ng, Maggie C.Y., Langefeld, Carl D., Divers, Jasmin, Lea, Janice P., Okusa, Mark D., Kimberly, Robert P., Bowden, Donald W., Freedman, Barry I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2015
Schlagworte:
Brief Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413768/
https://ncbi.nlm.nih.gov/pubmed/25249559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014050444
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