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A microfluidic device for epigenomic profiling using 100 cells
The sensitivity of chromatin immunoprecipitation (ChIP) assays poses a major obstacle for epigenomic studies of low-abundance cells. Here we present a microfluidics-based ChIP-Seq protocol using as few as 100 cells via drastically improved collection of high-quality ChIP-enriched DNA. Using this tec...
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| Veröffentlicht in: | Nat Methods |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4589469/ https://ncbi.nlm.nih.gov/pubmed/26214128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3488 |
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