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A microfluidic device for epigenomic profiling using 100 cells

The sensitivity of chromatin immunoprecipitation (ChIP) assays poses a major obstacle for epigenomic studies of low-abundance cells. Here we present a microfluidics-based ChIP-Seq protocol using as few as 100 cells via drastically improved collection of high-quality ChIP-enriched DNA. Using this tec...

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Bibliografski detalji
Izdano u:Nat Methods
Glavni autori: Cao, Zhenning, Chen, Changya, He, Bing, Tan, Kai, Lu, Chang
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589469/
https://ncbi.nlm.nih.gov/pubmed/26214128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3488
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