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Inhibition of the Aurora A kinase augments the anti-tumor efficacy of oncolytic measles virotherapy
Oncolytic measles virus (MV) strains have demonstrated broad spectrum preclinical anti-tumor, including breast cancer. Aurora A kinase controls mitotic spindle formation and plays a critical role in malignant transformation. We hypothesized that, by causing mitotic arrest, the Aurora A kinase inhibi...
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| Pubblicato in: | Cancer Gene Ther |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4589445/ https://ncbi.nlm.nih.gov/pubmed/26272026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2015.36 |
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