Macrophage-derived Tumor Necrosis Factor-α mediates diabetic renal injury

Monocyte/macrophage recruitment correlates strongly with the progression of diabetic nephropathy. Tumor necrosis factor-alpha (TNF-α) is produced by monocytes/macrophages but the direct role of TNF-α and/or macrophage-derived TNF-α in the progression of diabetic nephropathy remains unclear. Here we...

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Bibliographic Details
Published in:Kidney Int
Main Authors: Awad, Alaa S., You, Hanning, Gao, Ting, Cooper, Timothy K., Nedospasov, Sergei A., Vacher, Jean, Wilkinson, Patrick F., Farrell, Francis X., Reeves, W. Brian
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589442/
https://ncbi.nlm.nih.gov/pubmed/26061548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.162
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