Podocyte-specific chemokine (C-C motif) receptor 2 overexpression mediates diabetic renal injury in mice

Inflammation is a central pathophysiologic mechanism that contributes to diabetes mellitus and diabetic nephropathy. Recently, we showed that macrophages directly contribute to diabetic renal injury, and that pharmacological blockade or genetic deficiency of chemokine (C-C motif) receptor 2 (CCR2) c...

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Udgivet i:Kidney Int
Main Authors: You, Hanning, Gao, Ting, Raup-Konsavage, Wesley M., Cooper, Timothy K., Bronson, Sarah K., Reeves, W. Brian, Awad, Alaa S.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313320/
https://ncbi.nlm.nih.gov/pubmed/27914709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.09.042
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