SATB1 Mediates Long-Range Chromatin Interactions: A Dual Regulator of Anti-Apoptotic BCL2 and Pro-Apoptotic NOXA Genes

Aberrant expression of special AT-rich binding protein 1 (SATB1), a global genomic organizer, has been associated with various cancers, which raises the question of how higher-order chromatin structure contributes to carcinogenesis. Disruption of apoptosis is one of the hallmarks of cancer. We previ...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yang, Yin, Wang, Zongdan, Sun, Luan, Shao, Lipei, Yang, Nan, Yu, Dawei, Zhang, Xin, Han, Xiao, Sun, Yujie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589335/
https://ncbi.nlm.nih.gov/pubmed/26422397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139170
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