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Liver epithelial cells proliferate under hypoxia and protect the liver from ischemic injury via expression of HIF-1 alpha target genes

BACKGROUND: The remnant liver after extended liver resection is susceptible to ischemic injury, resulting in the failure of liver regeneration and liver dysfunction. The present study is aimed to investigate the protective role of the liver epithelial cells (LEC), a liver progenitor cell, on hepatoc...

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Bibliografische gegevens
Gepubliceerd in:Surgery
Hoofdauteurs: Abe, Yuki, Uchinami, Hiroshi, Kudoh, Kazuhiro, Nakagawa, Yasuhiko, Ise, Norihito, Watanabe, Go, Sato, Tsutomu, Seki, Ekihiro, Yamamoto, Yuzo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589249/
https://ncbi.nlm.nih.gov/pubmed/22575885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2012.03.003
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