Liver epithelial cells proliferate under hypoxia and protect the liver from ischemic injury via expression of HIF-1 alpha target genes

BACKGROUND: The remnant liver after extended liver resection is susceptible to ischemic injury, resulting in the failure of liver regeneration and liver dysfunction. The present study is aimed to investigate the protective role of the liver epithelial cells (LEC), a liver progenitor cell, on hepatoc...

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Dettagli Bibliografici
Pubblicato in:Surgery
Autori principali: Abe, Yuki, Uchinami, Hiroshi, Kudoh, Kazuhiro, Nakagawa, Yasuhiko, Ise, Norihito, Watanabe, Go, Sato, Tsutomu, Seki, Ekihiro, Yamamoto, Yuzo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589249/
https://ncbi.nlm.nih.gov/pubmed/22575885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2012.03.003
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