Interferon-λ and interleukin-22 cooperate for the induction of interferon-stimulated genes and control of rotavirus infection

The epithelium is the major entry point for many viruses but the processes protecting barrier surfaces against viral infections are incompletely understood. We identify interleukin (IL)-22 produced by group 3 innate lymphoid cells (ILC3s) as an amplifier of interferon (IFN)-λ signaling, a synergism...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Hernández, Pedro P., Mahlakoiv, Tanel, Yang, Ines, Schwierzeck, Vera, Nguyen, Nam, Guendel, Fabian, Gronke, Konrad, Ryffel, Bernhard, Hoelscher, Christoph, Dumoutier, Laure, Renauld, Jean-Christophe, Suerbaum, Sebastian, Staeheli, Peter, Diefenbach, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589158/
https://ncbi.nlm.nih.gov/pubmed/26006013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3180
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