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Increased Acetylation of Histone H4 at Lysine 12 (H4K12) in Monocytes of Transgenic Alzheimer’s Mice and in Human Patients

BACKGROUND: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by amyloid-β (Aβ) plaque formation, tau pathology, neurodegeneration and inflammatory processes. Monocytes are involved in inflammation in AD and are recruited to the diseased brain. Recently it has been shown that ab...

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Bibliographic Details
Published in:Curr Alzheimer Res
Main Authors: Plagg, Barbara, Ehrlich, Daniela, Kniewallner, Kathrin M., Marksteiner, Josef, Humpel, Christian
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589156/
https://ncbi.nlm.nih.gov/pubmed/26159193
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