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Localized smooth muscle differentiation is essential for epithelial bifurcation during branching morphogenesis of the mammalian lung
The airway epithelium develops into a treelike structure via branching morphogenesis. Here we show a critical role for localized differentiation of airway smooth muscle during epithelial bifurcation in the embryonic mouse lung. We found that during terminal bifurcation, changes in the geometry of na...
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| Veröffentlicht in: | Dev Cell |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4589145/ https://ncbi.nlm.nih.gov/pubmed/26387457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.08.012 |
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