Llwytho...

Determining exon connectivity in complex mRNAs by nanopore sequencing

Short-read high-throughput RNA sequencing, though powerful, is limited in its ability to directly measure exon connectivity in mRNAs that contain multiple alternative exons located farther apart than the maximum read length. Here, we use the Oxford Nanopore MinION sequencer to identify 7,899 ‘full-l...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Biol
Prif Awduron: Bolisetty, Mohan T., Rajadinakaran, Gopinath, Graveley, Brenton R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588896/
https://ncbi.nlm.nih.gov/pubmed/26420219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0777-z
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