Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation()

OBJECTIVE: Melanocortin-4 receptors (MC4Rs) are highly expressed by dopamine-secreting neurons of the mesolimbic tract, but their functional role has not been fully resolved. Voluntary wheel running (VWR) induces adaptations in the mesolimbic dopamine system and has a myriad of long-term beneficial...

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Publicado en:Mol Metab
Main Authors: Obici, Silvana, Magrisso, I. Jack, Ghazarian, Armen S., Shirazian, Alireza, Miller, Jonas R., Loyd, Christine M., Begg, Denovan P., Krawczewski Carhuatanta, Kimberly A., Haas, Michael K., Davis, Jon F., Woods, Stephen C., Sandoval, Darleen A., Seeley, Randy J., Goodyear, Laurie J., Pothos, Emmanuel N., Mul, Joram D.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588435/
https://ncbi.nlm.nih.gov/pubmed/26500841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.07.003
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