Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation()

OBJECTIVE: Melanocortin-4 receptors (MC4Rs) are highly expressed by dopamine-secreting neurons of the mesolimbic tract, but their functional role has not been fully resolved. Voluntary wheel running (VWR) induces adaptations in the mesolimbic dopamine system and has a myriad of long-term beneficial...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Obici, Silvana, Magrisso, I. Jack, Ghazarian, Armen S., Shirazian, Alireza, Miller, Jonas R., Loyd, Christine M., Begg, Denovan P., Krawczewski Carhuatanta, Kimberly A., Haas, Michael K., Davis, Jon F., Woods, Stephen C., Sandoval, Darleen A., Seeley, Randy J., Goodyear, Laurie J., Pothos, Emmanuel N., Mul, Joram D.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588435/
https://ncbi.nlm.nih.gov/pubmed/26500841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.07.003
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