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Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation()

OBJECTIVE: Melanocortin-4 receptors (MC4Rs) are highly expressed by dopamine-secreting neurons of the mesolimbic tract, but their functional role has not been fully resolved. Voluntary wheel running (VWR) induces adaptations in the mesolimbic dopamine system and has a myriad of long-term beneficial...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Mol Metab
Κύριοι συγγραφείς: Obici, Silvana, Magrisso, I. Jack, Ghazarian, Armen S., Shirazian, Alireza, Miller, Jonas R., Loyd, Christine M., Begg, Denovan P., Krawczewski Carhuatanta, Kimberly A., Haas, Michael K., Davis, Jon F., Woods, Stephen C., Sandoval, Darleen A., Seeley, Randy J., Goodyear, Laurie J., Pothos, Emmanuel N., Mul, Joram D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Elsevier 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588435/
https://ncbi.nlm.nih.gov/pubmed/26500841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.07.003
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