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Combined activation of the energy and cellular-defense pathways may explain the potent anti-senescence activity of methylene blue
Methylene blue (MB) delays cellular senescence, induces complex-IV, and activates Keap1/Nrf2; however, the molecular link of these effects to MB is unclear. Since MB is redox-active, we investigated its effect on the NAD/NADH ratio in IMR90 cells. The transient increase in NAD/NADH observed in MB-tr...
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| Publicado no: | Redox Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4588422/ https://ncbi.nlm.nih.gov/pubmed/26386875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.09.004 |
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