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Absence of somatic mutations of the mTOR gene in differentiated thyroid cancer
Thyroid cancer is the most common endocrine malignancy with increasing incidence. Mammalian target of rapamycin (mTOR) is an important downstream mediator of phosphatidylinositol 3-kinase (PI3K/Akt) signaling and regulates cell growth, apoptosis and metabolism. The mTOR gene is frequently mutated in...
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| Опубликовано в: : | Meta Gene |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4588405/ https://ncbi.nlm.nih.gov/pubmed/26504747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mgene.2015.08.005 |
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