Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis

Mitochondrial homeostasis is critical for tissue health, and mitochondrial dysfunction contributes to numerous diseases, including heart failure. Here, we have shown that the transcription factor Kruppel-like factor 4 (KLF4) governs mitochondrial biogenesis, metabolic function, dynamics, and autopha...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Liao, Xudong, Zhang, Rongli, Lu, Yuan, Prosdocimo, Domenick A., Sangwung, Panjamaporn, Zhang, Lilei, Zhou, Guangjin, Anand, Puneet, Lai, Ling, Leone, Teresa C., Fujioka, Hisashi, Ye, Fang, Rosca, Mariana G., Hoppel, Charles L., Schulze, P. Christian, Abel, E. Dale, Stamler, Jonathan S., Kelly, Daniel P., Jain, Mukesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588311/
https://ncbi.nlm.nih.gov/pubmed/26241060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79964
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