Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis

Mitochondrial homeostasis is critical for tissue health, and mitochondrial dysfunction contributes to numerous diseases, including heart failure. Here, we have shown that the transcription factor Kruppel-like factor 4 (KLF4) governs mitochondrial biogenesis, metabolic function, dynamics, and autopha...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Liao, Xudong, Zhang, Rongli, Lu, Yuan, Prosdocimo, Domenick A., Sangwung, Panjamaporn, Zhang, Lilei, Zhou, Guangjin, Anand, Puneet, Lai, Ling, Leone, Teresa C., Fujioka, Hisashi, Ye, Fang, Rosca, Mariana G., Hoppel, Charles L., Schulze, P. Christian, Abel, E. Dale, Stamler, Jonathan S., Kelly, Daniel P., Jain, Mukesh K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588311/
https://ncbi.nlm.nih.gov/pubmed/26241060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79964
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