Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis

Mitochondrial homeostasis is critical for tissue health, and mitochondrial dysfunction contributes to numerous diseases, including heart failure. Here, we have shown that the transcription factor Kruppel-like factor 4 (KLF4) governs mitochondrial biogenesis, metabolic function, dynamics, and autopha...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Liao, Xudong, Zhang, Rongli, Lu, Yuan, Prosdocimo, Domenick A., Sangwung, Panjamaporn, Zhang, Lilei, Zhou, Guangjin, Anand, Puneet, Lai, Ling, Leone, Teresa C., Fujioka, Hisashi, Ye, Fang, Rosca, Mariana G., Hoppel, Charles L., Schulze, P. Christian, Abel, E. Dale, Stamler, Jonathan S., Kelly, Daniel P., Jain, Mukesh K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588311/
https://ncbi.nlm.nih.gov/pubmed/26241060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79964
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