Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis

Mitochondrial homeostasis is critical for tissue health, and mitochondrial dysfunction contributes to numerous diseases, including heart failure. Here, we have shown that the transcription factor Kruppel-like factor 4 (KLF4) governs mitochondrial biogenesis, metabolic function, dynamics, and autopha...

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Gepubliceerd in:J Clin Invest
Hoofdauteurs: Liao, Xudong, Zhang, Rongli, Lu, Yuan, Prosdocimo, Domenick A., Sangwung, Panjamaporn, Zhang, Lilei, Zhou, Guangjin, Anand, Puneet, Lai, Ling, Leone, Teresa C., Fujioka, Hisashi, Ye, Fang, Rosca, Mariana G., Hoppel, Charles L., Schulze, P. Christian, Abel, E. Dale, Stamler, Jonathan S., Kelly, Daniel P., Jain, Mukesh K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588311/
https://ncbi.nlm.nih.gov/pubmed/26241060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79964
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