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Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages

The generation of an inflammatory environment is favorable and often decisive for the growth of both primary tumors and metastases. Tumor cells either express membrane molecules or release tumor-derived soluble factors able to alter myelopoiesis. Tumor-reprogrammed myeloid cells not only create a to...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Ugel, Stefano, De Sanctis, Francesco, Mandruzzato, Susanna, Bronte, Vincenzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588310/
https://ncbi.nlm.nih.gov/pubmed/26325033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80006
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