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Comparative genomics reveals multistep pathogenesis of E2A-PBX1 acute lymphoblastic leukemia
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer; however, its genetic diversity limits investigation into the molecular pathogenesis of disease and development of therapeutic strategies. Here, we engineered mice that conditionally express the E2A-PBX1 fusion oncogene, which re...
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| Publié dans: | J Clin Invest |
|---|---|
| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4588292/ https://ncbi.nlm.nih.gov/pubmed/26301816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81158 |
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