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cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-β-Induced Synapse Damage

A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate in Parkinson’s disease, also caused synapse d...

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Bibliografische gegevens
Gepubliceerd in:Biology (Basel)
Hoofdauteurs: Bate, Clive, Williams, Alun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588152/
https://ncbi.nlm.nih.gov/pubmed/26389963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology4030591
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