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Phospholipase A(2 )inhibitors protect against prion and Aβ mediated synapse degeneration
BACKGROUND: An early event in the neuropathology of prion and Alzheimer's diseases is the loss of synapses and a corresponding reduction in the level of synaptophysin, a pre-synaptic membrane protein essential for neurotransmission. The molecular mechanisms involved in synapse degeneration in t...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865460/ https://ncbi.nlm.nih.gov/pubmed/20374666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-13 |
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