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New drug target in protozoan parasites: the role of thioredoxin reductase

Amebiasis causes approximately 70,000 deaths annually and is the third cause of death due to parasites worldwide. It is treated primarily with metronidazole, which has adverse side effects, is mutagenic and carcinogenic, and emergence of resistance is an increasing concern. Unfortunately, better the...

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Vydáno v:Front Microbiol
Hlavní autoři: Andrade, Rosa M., Reed, Sharon L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588103/
https://ncbi.nlm.nih.gov/pubmed/26483758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00975
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