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New drug target in protozoan parasites: the role of thioredoxin reductase

Amebiasis causes approximately 70,000 deaths annually and is the third cause of death due to parasites worldwide. It is treated primarily with metronidazole, which has adverse side effects, is mutagenic and carcinogenic, and emergence of resistance is an increasing concern. Unfortunately, better the...

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Bibliografski detalji
Izdano u:Front Microbiol
Glavni autori: Andrade, Rosa M., Reed, Sharon L.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588103/
https://ncbi.nlm.nih.gov/pubmed/26483758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00975
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