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Uremic Toxins Induce ET-1 Release by Human Proximal Tubule Cells, which Regulates Organic Cation Uptake Time-Dependently

In renal failure, the systemic accumulation of uremic waste products is strongly associated with the development of a chronic inflammatory state. Here, the effect of cationic uremic toxins on the release of inflammatory cytokines and endothelin-1 (ET-1) was investigated in conditionally immortalized...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Schophuizen, Carolien M. S., Hoenderop, Joost G. J., Masereeuw, Rosalinde, van den Heuvel, Lambert P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588034/
https://ncbi.nlm.nih.gov/pubmed/26132391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells4030234
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