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Selection of a Hepatitis C Virus With Altered Entry Factor Requirements Reveals a Genetic Interaction Between the E1 Glycoprotein and Claudins

Hepatitis C virus (HCV) cell entry is a complex, multistep process requiring numerous host cell factors, including the tight junction protein claudin-1 (CLDN1). It is not known whether CLDN1 and the HCV glycoproteins physically interact. Therefore, the focus of this work was to study genetic interac...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Hopcraft, Sharon E., Evans, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587996/
https://ncbi.nlm.nih.gov/pubmed/25820616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27815
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