Specific interaction of hepatitis C virus glycoproteins with mannan binding lectin inhibits virus entry

Mannan-binding lectin (MBL) is a soluble innate immune protein that binds to glycosylated targets. MBL acts as an opsonin and activates complement, contributing to the destruction and clearance of infecting microorganisms. Hepatitis C virus (HCV) encodes two envelope glycoproteins E1 and E2, express...

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Bibliographic Details
Published in:Protein Cell
Main Authors: Brown, Kristelle S., Keogh, Michael J., Owsianka, Ania M., Adair, Richard, Patel, Arvind H., Arnold, James N., Ball, Jonathan K., Sim, Robert B., Tarr, Alexander W., Hickling, Timothy P.
Format: Artigo
Language:Inglês
Published: Higher Education Press 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875281/
https://ncbi.nlm.nih.gov/pubmed/21203938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0088-9
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