Involvement of Prolyl Hydroxylase Domain Protein in the Rosiglitazone-Induced Suppression of Osteoblast Differentiation

Rosiglitazone is a well-known anti-diabetic drug that increases insulin sensitivity via peroxisome proliferator-activated receptor γ (PPARγ) activation, but unfortunately it causes bone loss in animals and humans. A previous study showed that prolyl hydroxylase domain protein (PHD) plays a role in r...

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Publicado en:PLoS One
Autores principales: Kang, Ju-Hee, Kwak, Hyun Jeong, Choi, Hye-Eun, Kim, Juyoung, Hong, Sangmee, Kim, Ok-Hee, Oh, Byung Chul, Cheon, Hyae Gyeong
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587972/
https://ncbi.nlm.nih.gov/pubmed/26418009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139093
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