Predicting Anticancer Drug Responses Using a Dual-Layer Integrated Cell Line-Drug Network Model

The ability to predict the response of a cancer patient to a therapeutic agent is a major goal in modern oncology that should ultimately lead to personalized treatment. Existing approaches to predicting drug sensitivity rely primarily on profiling of cancer cell line panels that have been treated wi...

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Udgivet i:PLoS Comput Biol
Main Authors: Zhang, Naiqian, Wang, Haiyun, Fang, Yun, Wang, Jun, Zheng, Xiaoqi, Liu, X. Shirley
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587957/
https://ncbi.nlm.nih.gov/pubmed/26418249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004498
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