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Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles

Planar cell polarity (PCP) signaling controls the global orientation of surface structures, such as hairs and bristles, in both vertebrates and invertebrates. In Frizzled6 (-/-) (Fz6 (-/-)) mice, hair follicle orientations on the head and back are nearly random at birth, but reorient during early po...

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Pubblicato in:PLoS Genet
Autori principali: Chang, Hao, Cahill, Hugh, Smallwood, Philip M., Wang, Yanshu, Nathans, Jeremy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587951/
https://ncbi.nlm.nih.gov/pubmed/26418459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005532
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