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Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles

Planar cell polarity (PCP) signaling controls the global orientation of surface structures, such as hairs and bristles, in both vertebrates and invertebrates. In Frizzled6 (-/-) (Fz6 (-/-)) mice, hair follicle orientations on the head and back are nearly random at birth, but reorient during early po...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Chang, Hao, Cahill, Hugh, Smallwood, Philip M., Wang, Yanshu, Nathans, Jeremy
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587951/
https://ncbi.nlm.nih.gov/pubmed/26418459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005532
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