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Heat Shock Protein 60 in Eggs Specifically Induces Tregs and Reduces Liver Immunopathology in Mice with Schistosomiasis Japonica

BACKGROUND: Parasitic helminths need to suppress the host immune system to establish chronic infections. Paradoxically, immunosuppression induced by the worm also benefits the host by limiting excessive inflammation and tissue damage, which remains the major cause leading to serious morbidity and mo...

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Bibliographic Details
Published in:PLoS One
Main Authors: Zhou, Sha, Jin, Xin, Chen, Xiaojun, Zhu, Jifeng, Xu, Zhipeng, Wang, Xuefeng, Liu, Feng, Hu, Wei, Zhou, Liang, Su, Chuan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587937/
https://ncbi.nlm.nih.gov/pubmed/26418003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139133
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