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Nephrin Preserves Podocyte Viability and Glomerular Structure and Function in Adult Kidneys

Nephrin is required during kidney development for the maturation of podocytes and formation of the slit diaphragm junctional complex. Because nephrin expression is downregulated in acquired glomerular diseases, nephrin deficiency is considered a pathologic feature of glomerular injury. However, whet...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Li, Xuezhu, Chuang, Peter Y., D’Agati, Vivette D., Dai, Yan, Yacoub, Rabi, Fu, Jia, Xu, Jin, Taku, Oltjon, Premsrirut, Prem K., Holzman, Lawrence B., He, John Cijiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587684/
https://ncbi.nlm.nih.gov/pubmed/25644109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014040405
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