DCIR2(+) cDC2 DCs and Zbtb32 Restore CD4(+) T-Cell Tolerance and Inhibit Diabetes

During autoimmunity, the normal ability of dendritic cells (DCs) to induce T-cell tolerance is disrupted; therefore, autoimmune disease therapies based on cell types and molecular pathways that elicit tolerance in the steady state may not be effective. To determine which DC subsets induce tolerance...

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Bibliographic Details
Published in:Diabetes
Main Authors: Price, Jeffrey D., Hotta-Iwamura, Chie, Zhao, Yongge, Beauchamp, Nicole M., Tarbell, Kristin V.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2015
Subjects:
Immunology and Transplantation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587633/
https://ncbi.nlm.nih.gov/pubmed/26070317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1880
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