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Regulation of deoxynucleotide metabolism in cancer: novel mechanisms and therapeutic implications
Regulation of intracellular deoxynucleoside triphosphate (dNTP) pool is critical to genomic stability and cancer development. Imbalanced dNTP pools can lead to enhanced mutagenesis and cell proliferation resulting in cancer development. Therapeutic agents that target dNTP synthesis and metabolism ar...
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| Publicado no: | Mol Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4587406/ https://ncbi.nlm.nih.gov/pubmed/26416562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0446-6 |
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