Insights into the mechanisms, regulation, and therapeutic implications of extracellular matrix stiffness in cancer

Abstract The tumor microenvironment (TME) is critical for cancer initiation, growth, metastasis, and therapeutic resistance. The extracellular matrix (ECM) is a significant tumor component that serves various functions, including mechanical support, TME regulation, and signal molecule generation. Th...

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Bibliografiska uppgifter

Huvudupphov:	Ximo Zhang, Abdullah Al‐Danakh, Xinqing Zhu, Dan Feng, Linlin Yang, Haotian Wu, Yingying Li, Shujing Wang, Qiwei Chen, Deyong Yang
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Wiley 2025-01-01
Serie:	Bioengineering & Translational Medicine
Ämnen:	cancer ECM stiffness extracellular matrix signaling pathways targeted therapy tumor microenvironment
Länkar:	https://doi.org/10.1002/btm2.10698
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