Prooxidant and antioxidant properties of salicylaldehyde isonicotinoyl hydrazone iron chelators in HepG2 cells

BACKGROUND: Salicylaldehyde isonicotinoyl hydrazone (SIH) is an iron chelator of the aroylhydrazone class that displays antioxidant or prooxidant effects in different mammalian cell lines. Because the liver is the major site of iron storage, elucidating the effect of SIH on hepatic oxidative metabol...

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Pubblicato in:Biochim Biophys Acta
Autori principali: Caro, Andres A., Commissariat, Ava, Dunn, Caroline, Kim, Hyunjoo, García, Salvador Lorente, Smith, Allen, Strang, Harrison, Stuppy, Jake, Desrochers, Linda P., Goodwin, Thomas E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587295/
https://ncbi.nlm.nih.gov/pubmed/26275495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2015.08.005
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