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Sildenafil Attenuates Vaso-Obliteration and Neovascularization in a Mouse Model of Retinopathy of Prematurity

PURPOSE. We sought to determine the effect of sildenafil on retinal vascular changes in a mouse model of oxygen-induced retinopathy (OIR). METHODS. Vascular defects in OIR mice were quantified by measuring vaso-obliteration at postnatal days 12 and 17 (P12 and P17) and neovascularization at P17 to c...

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Bibliografiske detaljer
Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Fawzi, Amani A., Chou, Jonathan C., Kim, Gina A., Rollins, Stuart D., Taylor, Joann M., Farrow, Kathryn N.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586973/
https://ncbi.nlm.nih.gov/pubmed/24519428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13207
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