Photoreceptor oxidative stress in hyperoxia-induced proliferative retinopathy accelerates rd8 degeneration

To investigate the impact of photoreceptor oxidative stress on photoreceptor degeneration in mice carrying the rd8 mutation (C57BL/6N). We compared the hyperoxia-induced proliferative retinopathy (HIPR) model in two mouse strains (C57BL/6J and C57BL/6N). Pups were exposed to 75% oxygen, starting at...

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Bibliographic Details
Published in:PLoS One
Main Authors: Lajko, Michelle, Cardona, Herminio J., Taylor, Joann M., Farrow, Kathryn N., Fawzi, Amani A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495396/
https://ncbi.nlm.nih.gov/pubmed/28671996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180384
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