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Loop recognition and copper-mediated disulfide reduction underpin metal site assembly of Cu(A) in human cytochrome oxidase
Maturation of cytochrome oxidases is a complex process requiring assembly of several subunits and adequate uptake of the metal cofactors. Two orthologous Sco proteins (Sco1 and Sco2) are essential for the correct assembly of the dicopper Cu(A) site in the human oxidase, but their function is not ful...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586878/ https://ncbi.nlm.nih.gov/pubmed/26351686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505056112 |
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