Systematic analysis of asymmetric partitioning of yeast proteome between mother and daughter cells reveals “aging factors” and mechanism of lifespan asymmetry

Budding yeast divides asymmetrically, giving rise to a mother cell that progressively ages and a daughter cell with full lifespan. It is generally assumed that mother cells retain damaged, lifespan limiting materials (“aging factors”) through asymmetric division. However, the identity of these aging...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yang, Jing, McCormick, Mark A., Zheng, Jiashun, Xie, Zhengwei, Tsuchiya, Mitsuhiro, Tsuchiyama, Scott, El-Samad, Hana, Ouyang, Qi, Kaeberlein, Matt, Kennedy, Brian K., Li, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586869/
https://ncbi.nlm.nih.gov/pubmed/26351681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506054112
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