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Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum

Identification and genetic validation of new targets from available genome sequences are critical steps toward the development of new potent and selective antimalarials. However, no methods are currently available for large-scale functional analysis of the Plasmodium falciparum genome. Here we prese...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Garg, Aprajita, Wesolowski, Donna, Alonso, Dulce, Deitsch, Kirk W., Ben Mamoun, Choukri, Altman, Sidney
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586866/
https://ncbi.nlm.nih.gov/pubmed/26351679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515864112
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