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Reevaluating αE-catenin monomer and homodimer functions by characterizing E-cadherin/αE-catenin chimeras

As part of the E-cadherin–β-catenin–αE-catenin complex (CCC), mammalian αE-catenin binds F-actin weakly in the absence of force, whereas cytosolic αE-catenin forms a homodimer that interacts more strongly with F-actin. It has been concluded that cytosolic αE-catenin homodimer is not important for in...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Bianchini, Julie M., Kitt, Khameeka N., Gloerich, Martijn, Pokutta, Sabine, Weis, William I., Nelson, W. James
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586751/
https://ncbi.nlm.nih.gov/pubmed/26416960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201411080
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