CRISP1 as a novel CatSper regulator that modulates sperm motility and orientation during fertilization

Ca(2+)-dependent mechanisms are critical for successful completion of fertilization. Here, we demonstrate that CRISP1, a sperm protein involved in mammalian fertilization, is also present in the female gamete and capable of modulating key sperm Ca(2+) channels. Specifically, we show that CRISP1 is e...

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Udgivet i:J Cell Biol
Main Authors: Ernesto, Juan I., Weigel Muñoz, Mariana, Battistone, María A., Vasen, Gustavo, Martínez-López, Pablo, Orta, Gerardo, Figueiras-Fierro, Dulce, De la Vega-Beltran, José L., Moreno, Ignacio A., Guidobaldi, Héctor A., Giojalas, Laura, Darszon, Alberto, Cohen, Débora J., Cuasnicú, Patricia S.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586743/
https://ncbi.nlm.nih.gov/pubmed/26416967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412041
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