CatSper channels are regulated by protein kinase A

Mammalian sperm must undergo capacitation as a preparation for entering into hyperactivated motility, undergoing the acrosome reaction, and acquiring fertilizing ability. One of the initial capacitation events occurs when sperm encounter an elevated HCO(3)(−) concentration. This anion activates the...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Orta, Gerardo, de la Vega-Beltran, José Luis, Martín-Hidalgo, David, Santi, Celia M., Visconti, Pablo E., Darszon, Alberto
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204891/
https://ncbi.nlm.nih.gov/pubmed/30213858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001566
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