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Targeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor Immunity

Transcription is a dynamic process influenced by the cellular environment: healthy, transformed, and otherwise. Genome-wide mRNA expression profiles reflect the collective impact of pathways modulating cell function under different conditions. In this review we focus on the transcriptional pathways...

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Pubblicato in:Vaccines (Basel)
Autori principali: Waugh, Katherine A., Leach, Sonia M., Slansky, Jill E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586477/
https://ncbi.nlm.nih.gov/pubmed/26393659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines3030771
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