Bromodomain inhibitors regulate the C9ORF72 locus in ALS

A hexanucleotide repeat expansion residing within the C9ORF72 gene represents the most common known cause of amyotrophic lateral sclerosis (ALS) and places the disease among a growing family of repeat expansion disorders. The presence of RNA foci, repeat-associated translation products, and sequestr...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Zeier, Zane, Esanov, Rustam, Belle, Kinsley C., Volmar, Claude-Henry, Johnstone, Andrea L., Halley, Paul, DeRosa, Brooke A., Khoury, Nathalie, van Blitterswijk, Marka, Rademakers, Rosa, Albert, Jeffrey, Brothers, Shaun P., Wuu, Joanne, Dykxhoorn, Derek M., Benatar, Michael, Wahlestedt, Claes
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586400/
https://ncbi.nlm.nih.gov/pubmed/26099177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.06.017
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